منابع مشابه
Molecular Testing of Brain Tumor
The World Health Organization (WHO) classification of central nervous system (CNS) tumors was revised in 2016 with a basis on the integrated diagnosis of molecular genetics. We herein provide the guidelines for using molecular genetic tests in routine pathological practice for an accurate diagnosis and appropriate management. While astrocytomas and IDH-mutant (secondary) glioblastomas are chara...
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There are significant challenges associated with qualitative and quantitative nucleic acid tests performed in diagnostic laboratories. The development of internationally available certified reference materials which can be traced to reference measurements will contribute to a better understanding of the performance characteristics of nucleic acid tests and enhance reliability and comparability ...
متن کاملMolecular Culprits Generating Brain Tumor Stem Cells
Despite current advances in multimodality therapies, such as surgery, radiotherapy, and chemotherapy, the outcome for patients with high-grade glioma remains fatal. Understanding how glioma cells resist various therapies may provide opportunities for developing new therapies. Accumulating evidence suggests that the main obstacle for successfully treating high-grade glioma is the existence of br...
متن کاملAn overview of therapeutic approaches to brain tumor stem cells
Primary and secondary malignant central nervous system (CNS) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. Glioblastoma multiform (GBM), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced DNA damage repair program that also induces recurrence and resists current chemo- and radi...
متن کاملDiagnosis of brain tumor using PNN neural networks
Cells grow and then need a very neat method to create new cells that work properly to maintain the health of the body. When the ability to control the growth of the cells is lost, they are unconsidered and often divided without order. Exemplified cells form a tissue mass called the tumor. In fact, brain tumors are abnormal and uncontrolled cell proliferations. Segmentation methods are used in b...
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ژورنال
عنوان ژورنال: Journal of Pathology and Translational Medicine
سال: 2017
ISSN: 2383-7837,2383-7845
DOI: 10.4132/jptm.2017.03.08